1890 Raimundo Irineu Serra, more commonly known as “Master Irineu,” founder of the Santo Daime tradition, was born in Brazil .

(c.) 1914 Irineu Serra drank ayahuasca for the first time in the Amazon frontier of Brazil, Bolivia and Peru.

1930 The first “work” or ritual (trabalho) of the Santo Daime took place in Rio Branco, Brazil.

1965 Sebastião Mota de Melo (commonly known as “Padrinho Sebastião”) met Mestre Irineu for the first time.

1971 Mestre Irineu died.

1975 CEFLURIS held its first official work at Colônia Cinco Mil.

1982 Céu do Mar, the first church of the Santo Daime in the south of Brazil, opened under the leadership of Paulo Roberto Silva e Souza.

1983 Céu do Mapiá, which later became the official headquarters of CEFLURIS, opened.

1990 Padrinho Sebastião died. His son, Alfredo Gregório de Melo (Padrinho Alfredo) assumed command of CEFLURIS.

2009 A U.S. District Judge ruled that the DEA is explicitly prohibited from “penalizing the sacramental use of Daime tea” by practitioners of the Santo Daime in Oregon.